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Baba Y, Higa JK, Shimada BK, Horiuchi KM, Suhara T, Kobayashi M, Woo JD, Aoyagi H, Marh KS, Kitaoka H, et al

Vitamin B12 is an essential nutrient involved in energy production, red blood cell formation, and nervous system function

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This articles describes the synthesis of a synthetic hydrogel capable of incorporating the complex signals of native bone marrow through a mixture of multiple peptide epitopes

Short answer: cycling is the reasonable approach, but not for the dramatic reasons people usually give